Shandon Cryotome Cryostat Series


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Shandon Cryotome® Cryostat Series

Shandon Cryotome FSE Shandon Cryotome FE Shandon Cryotome SME

Analyze • Detect • Measure • Control™

Shandon Cryotome® FE and FSE
Designed with your needs in mind.

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The 5th generation of Shandon Cryotomes are precision engineered, ergonomic instruments designed to meet the needs of all clinical settings, producing high quality frozen sections with less fatigue. The spacious chamber, colored cryocassettes, and superior knife holder design assist the user in producing excellent frozen sections that are easily obtained and quickly identifiable.

• Adapts to multiple users and samples.

• Rapid temperature response reduces turn-around time.

• Built-in operator comfort.

* Unit shown with consumables which are sold separately.

• Reliability and safety provide added peace-ofmind.

Ease of Use: Adapts to User Expertise • Microtome outside the cryochamber makes it easier and quicker to clean. • Simple, intuitive, multi-lingual, touch-screen display for easy instrument operation. • Complete temperature controls on the main touch-screen display. • Color-coded levers and graphics make knifeholder adjustments obvious. • Angle of clamp plate enables easy specimen pick-up. • Easy to use anti-roll plate (glass or plastic).

Peace of Mind • Dual compressor system ensures specimen integrity by keeping specimens frozen if
the cryobar fails. • Remote Alarm alerts user in case of system failure. • Multi-level security code protection prevents unauthorized access and protocol
alterations to the Cryotome.

NEW BLADE HOLDER: Lateral movement of blade holder eliminates
need to unclamp and re-clamp blade. Maximizes blade usage.
Color coded levers identify lever functions.

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Faster Specimen Turn-Around Time
• Microtome outside the cryochamber allows faster temperature adjustment.
• Cryobar with adjustable temperature controls and dedicated cryobar refrigeration system (0º C to -55º C or colder with the boost feature) rapidly cools specimen to help prevent freezing artifact.
• Specimen holder temperature control (FSE only) allows for enhanced sectioning of a variety of tissue types.
• Shandon Cryotome® cools rapidly from ambient to set temperature in as little as 2 hours.
• Easy removal of frozen specimen from the cryocassette with the "Quick-heated" specimen release feature.

Ergonomics
• The three-level adjustable footrest provides greater comfort and helps reduce fatigue whether sitting or standing.
• The rounded exterior edges, the raised cutting area, and the footrest provide comfort while sectioning by eliminating back strain and fatigue.
• Various sized shelves allow the user to arrange working layout inside the chamber to suit their individual needs.

Safety and Security • Microtome outside the chamber allows easy
decontamination and cleaning. • Positive-locking flywheel prevents injury while working
around blade and specimen. • CFC-free refrigerant and foam insulation. • Automated fumigation cycle to disinfect the cryochamber.

MICROTOME OUTSIDE OF CRYOCHAMBER: Allows for easy decontamination and
cleaning. Faster temperature adjustment.

SPACIOUS CRYOCHAMBER AND COLOR-CODED CRYOCASSETTES: Facilitates easy patient / specimen identification.

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Shandon Cryotome® FSE / FE Cryostat Series Specifications

Description Shandon Cryotome FE Shandon Cryotome FE Shandon Cryotome FSE Shandon Cryotome FSE

230V, 50Hz 115V, 60Hz 230V, 50Hz 115V, 60Hz

Order Number A78900001 A78900002 A78900003 A78900004

Physical Specifications

Dimensions (H x W x D)

49.2” x 27.8” (+ 5” for handle) x 29.3” (125 max. x 70.5 (+ 12.5 cm) x 74.5 cm)

WORKING HEIGHT: 41” (105 cm) max.

CHAMBER ACCESS WIDTH: 19.7” (50 cm) min.

Weight

275.6 lbs. (125 kg)

Power Requirements

1800VA (220-240 Vac); 6,147 BTU/Hr

1800VA (110-120 Vac); 6,147 BTU/Hr

Microtome

Section Thickness Adjustment

1 to 20µm in 1µm increments

20 to 60µm in 5µm increments

Total horizontal specimen advance

25mm

Cutting Stroke

57mm

Trim wheel

8µm indents

Motorized Coarse Advance

1mm/sec

Specimen Retraction Standard

Refrigeration

Cryochamber

0ºC to -35ºC

Cryobar

0ºC to -55ºC or colder

(with boost facility)

Specimen Head (FSE only):

0ºC to -45ºC (within +/- 10ºC of

chamber temperature)

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SHANDON CRYOTOME FSE / FE / SME BLADE HOLDERS Specify at the time of order.
SEE PAGE 9 for detailed ordering information.

Included with Cryotome

Specimen Head (FSE) - X-Y Orientation head with specimen temperature control

Specimen Head (FE) - X-Y Orientation head without specimen temperature control

Cryocassettes - Variety of sizes and styles

Cryobar with cryocassette identifier – 6 positions, 6 heat sink block

positions (variable weights), and plastic cover (stops excessive frost build up)

Footrest - adjustable to 3 positions

Lockable Heated Window

Heat Extractors (one each standard weight, half-weight, and double weight)

Specimen and Tool Storage Shelves

Debris Tray and Brush

Touch Screen Display

Operator Manual (Specify Language)

A78910100

Specify Knife Holder at the time of order.

SEE PAGE 9.

* Contents, Packaging, and Quantities of items listed under “Included with Product” are subject to change without prior notice.

Available Accessories

Order Number

Low Profile Disposable Blade Holder

See Page 9

High Profile Disposable Blade Holder

See Page 9

Universal Blade Holder

See Page 9

Glass Anti-roll Plate

A78930200

Plastic (perspex) Anti-roll Plate

A78910075

XY orientation head [FE only]

A78910016

Cryobar Cassette Identification Label - 4/pk.

A78910054

Cryobar Cover

A78910041

Cryocassette - 40mm diameter crosshatched - 6/Pk.

A78910031

(multi-colored)

Shandon Cryocassette, 25 mm annular, 4 / Pk. (with handle) 77210150

Shandon Cryocassette, 35 mm annular, 4 / Pk. (with handle) 77210151

Shandon Cryocassette, 45 mm annular, 4 / Pk. (with handle) 77210152

Shandon Cryocassette, 9.5 mm annular, 4 / Pk. (with handle) 77210153

Cryocassette - 40mm diameter annular - 4/Pk. (not shown) A78910055

Cryocassette - 25 mm diameter crosshatched - 4/Pk.

A78910056

Cryocassette - 28 x 40mm crosshatched - 4/Pk.

A78910057

Handle - 4/Pk.

A78910058

Debris tray

A78910039

Heat Extractor - Standard

A78910014

Heat Extractor - Half-weight

A78910036

Heat Extractor - Double-weight

A78910037

Tool Shelf - 60 mm width

A78930121

Narrow Shelf - 56 mm width

A78930166

Wide Shelf - 80 mm width

A78930063

Wide Brush (Debris)

P12257

Narrow Brush (Sections)

P12940

#4 Camel Hair Brush (see page 12)

1910

Shandon Cryotome FSE Gold Service Plan (see page 16)

A78900004C

Shandon Cryotome FSE Bronze Service Plan (see page 16)

A78900004CPM

Shandon Cryotome FE Gold Service Plan (see page 16)

A78900002C

Shandon Cryotome FE Bronze Service Plan (see page 16)

A78900002CPM

Agency Approvals Designed to meet IEC 61010, CSA, UL, and CE Mark (IVDD compliant).

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Shandon Cryotome® Cryocassettes
Cryocassettes for the Shandon Cryotome FSE / FE / SME cryostats.

A78910031 40 mm Cross-hatch Multi-colored 6 / Pk.

77210150* Annular 25 mm 4 / Pk.

77210151* Annular 35 mm 4 / Pk.

77210152* Annular 45 mm 4 / Pk.

77210153* Annular 9.5 mm 4 / Pk.

A78910057 28 x 40 mm Cross-hatch
4 / Pk.

A78910056 25 mm
Cross-hatch 4 / Pk.

* One each supplied in Variety Pack 77210154.
NOTE: Shandon Cryotome FSE / SME has specimen holder components pre-mounted in cryochamber (cryocassette clamp, XY orienting head, and peltier). These components are replaceable only through Thermo Electron Corp., Anatomical Pathology Service Department. Call for details.

A78910058
Cryocassette Handle
4 / Pk.

Shandon Cryotome E Cryocassettes and Accessories – see Anatomical Pathology Product Catalog for complete ordering information.

Suggested Cutting Temperatures for Frozen Tissue

Tissue Type
UNFIXED TISSUE Brain Liver Lymph Nodes Kidney Spleen Muscle Thyroid Skin Breast Breast with Fat Adipose Tissue
FIXED TISSUE

Chamber Temperature (˚C)
-12˚ -14˚ -14˚ -16˚ -16˚ -20˚ -20˚ -25˚ -25˚ -30˚ or below -30˚ or below -12˚ to -17˚

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Shandon Cryotome® SME Cryostat
Fully automated cryostat.

Spacious Cryochamber • Cryochamber temperature to -30°C. • Operator controls microtome movement
from outside of cryochamber. • Open-top design minimizes
temperature gain during prolonged use. • Well-illuminated, stainless steel
chamber. • CFC-free refrigerant and foam
insulation. • Accessories in the cryochamber are
removable for easy cleaning and disinfecting of the chamber. • Automatic programmable defrost. • Automatic programmable formaldehyde fumigation.
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Safety • Features formaldehyde fumigation
for the cryochamber – a method proven effective against tuberculosis and many other known pathogens. • Fumigation and defrost may be activated instantly or programmed to delay. • The cryochamber window automatically locks during formaldehyde fumigation. • Waste fluids drain efficiently into easy-access collection jar. • Positive-locking flywheel with 3position lock. • Locking, frost-free window places a barrier between the operator and the specimen. • Features an emergency stop button.
Peltier Controls • Peltier-controlled cold spot on the
Cryobar aids quick-freezing to -60° C, reducing ice crystal artifact formation. • Peltier-controlled specimen head to ± 10˚ C of chamber temperature.

Microtome Features
• Microtome is housed outside the cryochamber for easy cleaning and maintenance.
• Precision microtome has a light, balanced feel over the complete travel range.
• Shandon Cryotome SME features ACCU-FEED system with 25,000 µm advance that may be set at 1-20µm intervals in 1 µm increments and 20-60µm intervals at 5µm increments
• 360° specimen orientation capability.

Shandon Cryotome® SME Cryostat Series Specifications

Description

Order Number

Shandon Cryotome SME

110-120V, 60Hz

77200002

Shandon Cryotome SME

220-240V, 50Hz

77200001

German and French keyboards are available. Contact your sales representative for

details.

Physical Specifications Dimensions (H x W x D) 42.5” x 26” x 25.5” (107 x 66 x 64 cm) Weight 330 lbs. (150 kg) Power Requirements 1400VA (220-240 Vac) 1700VA (110-120 Vac)

Control Panel • Shandon Cryotome SME cryostat features microprocessor-
based, touch-key controls with specimen travel graphic indicator, clear digital displays of cryochamber and cryobar temperatures.
Accessories • Select from universal blade holder, high-profile disposable blade
holder, or low-profile disposable blade holder. • High and low-profile blade holder includes an easy-to-use, glass
anti-roll plate. • Universal blade holder includes a plastic anti-roll plate. • XY orientation head is standard.

Included with Shandon Cryotome SME*

Order Number

XY Orientation head with specimen temperature control

Included

Debris Tray

0620-004

Storage Shelf

0620-002

Shandon Cryocassette, 35 mm annular, 4 / Pk. (with handle) 77210151

Shandon Cryocassette, variety pack

77210154

1 ea. 10, 25, 25, 45 mm annular with 2 handles

Footswitch

77220533

Operator Manual (specify language)

77210160

Service Record Book

A77210167

* Contents, Packaging, and Quantities of items listed under “Included with Product” are subject to change without prior notice.

Available Accessories for Shandon Crytome SME Order Number

Shandon Low Profile Disposable Blade Holder

See Page 9

Shandon High Profile Disposable Blade Holder

See Page 9

Shandon Universal Blade Holder

See Page 9

Cryocassette - 40mm diameter crosshatched - 6/Pk.

A78910031

(multi-colored)

Shandon Cryocassette, 25 mm annular, 4 / Pk. (with handle) 77210150

Shandon Cryocassette, 35 mm annular, 4 / Pk. (with handle) 77210151

Shandon Cryocassette, 45 mm annular, 4 / Pk. (with handle) 77210152

Shandon Cryocassette, 9.5 mm annular, 4 / Pk. (with handle) 77210153

Cryocassette - 40mm diameter annular - 4/Pk.

A78910055

Cryocassette - 25 mm diameter crosshatched - 4/Pk.

A78910056

Cryocassette - 28 x 40mm crosshatched - 4/Pk.

A78910057

Handle - 4/Pk.

A78910058

Shandon MOHS Organizer Tray

77230046

Replacement Handles for SME Cryocassettes

77220537

Plastic Knife Guard

A77210064

Glass Anti-Roll Plate

A78930200

Service Manual (Specify Language)

77210166

Shandon Cryotome SME Gold Service Plan (see page 16)

1196101

Shandon Cryotome SME Bronze Service Plan (see page 16)

1196101PM

Agency Approvals Designed to meet IEC 61010, CSA, UL, and CE Mark (IVDD compliant).

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Shandon Cryotome® Accessories

A78910014 Heat Extractor Standard Shandon Cryotome FSE / FE ONLY

A78910037 Heat Extractor Double-weight Shandon Cryotome FSE / FE ONLY

A78910036 Heat Extractor Half-weight Shandon Cryotome FSE / FE ONLY

A78930200
Glass Anti-roll Plate

A77210064
Plastic Knife Guard

P12940 Narrow Brush

P12257 Wide Brush

A78910041 Cryobar Cover Shandon Cryotome FSE / FE ONLY
A78910054 Cryobar Cassette Identification Label - 4 / Pk.
Shandon Cryotome FSE / FE ONLY
A78910039 Debris Tray Shandon Cryotome FSE / FE ONLY
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A78930121 Tool Shelf Shandon Cryotome FSE / FE ONLY
A78930063 Wide Shelf Shandon Cryotome FSE / FE ONLY
A78930166 Narrow Shelf Shandon Cryotome FSE / FE ONLY

Shandon Cryotome® Blade Holders
Blade holders for the Shandon Cryotome FSE / FE and SME / E.

Shandon Universal Blade Holder

• Accepts standard “C” or “D” profile knife up to 220 mm. (120 mm is standard length.)
• May be used with standard steel knives or with disposable blade holder.
• Use in conjunction with Disposable Blade Holders Part Nos. 40 or No. 47. See Page 11.

Description Shandon Universal Cryotome Blade Holder

Order Number A78910047

Shandon Low-Profile Blade Holder
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• Lateral movement of blade holder eliminates need to unclamp and re-clamp blade.
• Color coded levers identify lever functions. • Use with low-profile disposable blades. See Page 10.

Description Shandon Low Profile Cryotome Blade Holder Base and Top Stage

Order Number A78910032

Shandon High-Profile Blade Holder

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• Lateral movement of blade holder eliminates need to unclamp and re-clamp blade.
• Color-coded levers identify lever functions.

• This holder will accept either standard or heavy-duty high-profile blades, providing a wide range of tissue sectioning. See Pages 10 and 11.

Description Shandon High Profile Cryotome Blade Holder

Order Number A78910033

Shandon Cryostat Lubricating Oil
• Available in 4 oz. (118 ml) bottle.

Description Shandon Cryostat Lubricating Oil

Pkg/Qty Each

Order Number 291

Shandon MOHS Organizer Tray
• Holds multiple cryocassettes for better organization of specimens.
• Measures 10.5” x 4.7” (26.6 x 11.9 cm).
• For use in Shandon Cryotome SME.

Description Shandon Mohs Organizer Tray

Order Number 77230046

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Disposable Blades

Low Profile
Description
Shandon MB DynaSharp™ NNEEWW Low-Profile Disposable Blade
80 x 8 x 0.25 mm 34° Facet Angle

Benefits
Ribbons well from initial cut. Best for derm and biopsy tissues. Increased sharpness lowers friction during sectioning. Quickly reaches optimal performance.

+ Shandon MX35
Premier Low-Profile Disposable Blade
80 x 8 x 0.25 mm 34° Facet Angle

Increased durability. Increased sharpness lowers friction and lessens resistance during sectioning. Reduces blade usage.

Shandon MX35 Premier Low-Profile Disposable Blade
80 x 8 x 0.25 mm 34° Facet Angle

Durable – longer blade life Longer optimal sectioning performance.

Shandon MB35 Premier Low-Profile Disposable Blade
80 x 8 x 0.25 mm 34° Facet Angle
Shandon MB22 Premier Low-Profile Disposable Blade
80 x 8 x 0.25 mm 22° Facet Angle

Ribbons well from initial cut. Well suited for routine sectioning. Quickly reaches optimal performance.
Excellent for needle biopsies of kidney and liver. Quickly reaches optimal sectioninng performance. Use where 1 - 2 micron sections are desired.

High Profile Description

Benefits

Shandon HP35 High Profile Disposable Blade with PTFE Coating
75 x 14 x 0.31 mm 34° Facet Angle

Durable – longer blade life
Quickly reaches optimal sectioning performance.

Shandon HP35n High Profile Disposable Blade without PTFE Coating
75 x 14 x 0.31 mm 34° Facet Angle

Increased durability. Low cost.

Structure of a Blade Edge

Superior Edge Profile
The shape of the blade edge is optimized to provide excellent sectioning performance, ensuring easier ribboning and improved sharpness.

EDGE-GRINDING FACE

TIP OF THE EDGE

1st FACET

2nd FACET

3rd FACET

Coating
Coating is optimized to provide durability and easy ribboning.

C

B

A

BLADE THICKNESS

Description Shandon MB DynaSharp Low Profile Shandon MX-35 Premier+ Low Profile Shandon MX-35 Premier Low Profile Shandon MB-35 Premier Low Profile Shandon MB-22 Premier Low Profile Shandon HP-35 Coated High Profile Shandon HP-35n High Profile

Pkg/Qty 50 / Pk. 50 / Pk. 50 / Pk. 50 / Pk. 50 / Pk. 50 / Pk. 50 / Pk.

Order Number 3050836 3052835 3051835 3050835 3050822 3150734 3152735

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Shandon Cryotome Cryostat Series