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Department of Higher Education Government of Uttar Pradesh Lucknow
National Education Policy-2020
Common Minimum Syllabus for all UP State Universities and Colleges For First Three Years of Higher Education (UG)
Proposed Titles for Theory and Practical Papers Under Graduate Programme SUBJECT: ZOOLOGY
Dr. Monisha Banerjee Professor& Dean Research Molecular & Human Genetics Lab
Department of Zoology University of Lucknow, Lucknow
Dr. Samar Vir Singh Rathore Assistant Professor
Department of Zoology St. John’s College Agra, UP
1
Dr. Praveen Ojha Sr. Assistant Professor Department of Zoology Kishori Raman PG College
Mathura, UP
Name
Designation
Steering Committee
Mrs. Monika S. Garg, (I.A.S.) Additional Chief Secretary
Chairperson Steering
Committee
Prof. Poonam Tandan
Professor,
Dept. of Physics
Prof. Hare Krishna
Professor,
Dept. of Statistics
Dr. Dinesh C. Sharma
Associate Professor,
Dept. of Zoology
Supervisory Committee-Science Faculty
Dr. Vijay Kumar Singh
Associate Professor,
Dept. of Zoology
Dr. Santosh Singh
Dean,
Dept. of Agriculture
Dr. Baby Tabussam
Associate Professor,
Dept. of Zoology
Dr. Sanjay Jain
Associate Professor,
Dept. of Statistics
Syllabus Developed by:
Affiliation Dept. of Higher Education U.P., Lucknow
Lucknow University, U.P. CCS University Meerut, U.P. K.M. Govt. Girls P.G. College Badalpur, G.B. Nagar, U.P. Agra College, Agra Mahatma Gandhi Kashi Vidhyapeeth, Varanasi Govt. Raza P.G. College Rampur, U.P. St. John’s College, Agra
S.No. 1.
2. 3.
Name
Designation
Department College/University
Dr. Monisha Banerjee
Professor & Dean,
Zoology
University of Lucknow,
Research
Lucknow
Dr. Samar Vir Singh Rathore Assistant Professor
Zoology
St. John’s College, Agra
Dr. Praveen Ojha
Assistant Professor
Zoology
Kishori Raman PG College,
Mathura
Semester-wise Titles of the Papers in B.Sc (Zoology)
Year Sem.
1
I
II
2
III
IV
3
V
VI
Course Code B050101T B050102P B050201T B050202P/R
B050301T B050302P B050401T
B050402P/R
B050501T
B050502T B050503P
B050601T B050602T B050603P
Paper Title Cytology, Genetics and Infectious Diseases
Cell Biology and Cytogenetics Lab Biochemistry and Physiology Physiological, Biochemical &Hematology Lab
Molecular Biology, Bioinstrumentation &Biotechniques Bioinstrumentation& Molecular Biology Lab Gene Technology, Immunology and Computational Biology Genetic Engineering and Counselling Lab
Diversity of Non-Chordates, Parasitology and Economic Zoology Diversity of Chordates and Comparative Anatomy Lab on Virtual Dissection, Anatomy, Economic Zoology and Parasitology Evolutionary and Developmental Biology Ecology, Ethology, Environmental Science and Wildlife Lab on Environmental Science, Behavioral Ecology, Developmental Biology, Wildlife, Ethology
Theory/Practical Theory
Practical Theory Practical/Field work Theory Practical Theory
Practical/Field work Theory
Theory Practical
Theory Theory Practical
Credits 04 02 04 02
04 02 04
02
04
04 02
04 04 02
2
Proposed Year wise Structure of UG Program in Zoology
Programme/Year
1 Certificate Course in
Medical Diagnostics & Public Health
Semester I
II
Course Codes B050101T
B050102P B050201T
B050202P/R
Paper Title
Cytology, Genetics and Infectious Diseases Cell Biology & Cytogenetics Lab Biochemistry and Physiology
Physiological, Biochemical &Hematology Lab
Credits 04 02 04
02
2 Diploma in Molecular Diagnostics and
Genetic Counselling
3 Degree in Bachelor of Science
B050301T
Molecular Biology,
Bioinstrumentation &
04
III
Biotechniques
B050302P
Bioinstrumentation &
Molecular Biology Lab
02
B050401T
Gene Technology, Immunology
and Computational Biology
04
IV
B050402P/R Genetic Engineering and
Counselling Lab
02
B050501T
Diversity of Non-Chordates,
Parasitology and Economic
04
Zoology
V
B050502T
Diversity of Chordates and
Comparative Anatomy
04
B050503P
Lab on Virtual Dissection,
Anatomy, Economic Zoology 02
and Parasitology
B050601T
Evolutionary and
Developmental Biology
04
VI
B050602T
Ecology, Ethology,
Environmental Science and
04
Wildlife
B050603P
Lab on Environmental Science,
Behavioral Ecology,
Developmental Biology,
02
Wildlife, Ethology
Teaching Hours
60 60 60 60
60 60 60 60 60 60 60
60
60
60
3
Subject prerequisite To study Zoology in undergraduate, a student must have studied Biology, Biotechnology or Life Science in Class 12.
Programme Objectives (POs)
1. The programme has been designed in such a way so that the students get the flavour of both classical and modern aspects of Zoology/Animal Sciences. It aims to enable the students to study animal diversity in Indian subcontinent, environmental science and behavioural ecology.
2. The modern areas including cell biology and genetics, molecular biology, biochemistry, physiology followed by biostatistics, Evolutionary biology, bioinformatics and genetic engineering have been included to make the study of animals more interesting and relevant to human studies which is the requirement in recent times.
3. The lab courses have been designed in such a way that students will be trained to join public or private labs.
PSO1
PSO 2 PSO 3 PSO 4
PSO 5
Certificate Course in Medical Diagnostics & Public Health
B.Sc I Programme Specific Outcomes (PSOs) This course introduces System Biology and various functional components of an organism. Emphasis will be on physiological understanding abnormalities and anomalies associated with white blood cells and red blood cells. The course emphasizes cell identification, cell differentiation and cell morphology evaluation procedures. This will enhance hematology analytical skills along with skill of using many instruments. The students will learn the basic principles of genetics and how to prepare karyotypes to study the chromosomes. How chromosomal aberrations are inherited in humans by pedigree analysis in families. The students will have hands-on training in the techniques like microscopy, centrifugation and chromatography, and various biochemical techniques, preparation of slides which will help them in getting employment in pathology labs and contribute to health care system. The Certificate courses will enable students to apply for technical positions in government and private labs/institutes.
4
PSO1 PSO 2 PSO 3 PSO 4
PSO 5
Diploma in Molecular Diagnostics and Genetic Counselling
B.Sc II Programme Specific Outcomes (PSOs) The student at the completion of the course will be able to have a detailed and conceptual understanding of molecular processes viz. DNA to trait. The differential regulation of genes in prokaryotes and eukaryotes leads to the development of an organism from an embryo. The students will be able to understand and apply the principles and techniques of molecular biology which prepares students for further career in molecular biology. Independently execute a laboratory experiment using the standard methods and techniques. The principles of genetic engineering, gene cloning, immunology and related technologies will enable students to play an important role in applications of biotechnology in various fields like agriculture, forensic sciences, industry and human health and make a career out of it. Students can have their own start-ups as well. The basic tools of bioinformatics will enable students to analyze large amount of genomic data and its application to evolutionary biology.Apply knowledge and awareness of the basic principles and concepts of biology, computer science and mathematics existing software effectively to extract information from large databases and to use this information in computer modeling. The Diploma courses will ensure employability in Hospitals/Diagnostics and Pathology labs with good hands-on training. It will also enable students to take up higher studies and Research as their career and work in renowned labs in the country and abroad.
5
PSO1 PSO 2 PSO 3
PSO 4 PSO 5 PSO 6
PSO 7
Degree in Bachelor of Science
B.Sc III Programme Specific Outcomes (PSOs) This programme aims to introduce students to animal diversity of
invertebrates and vertebrates. The students will be taught about invertebrates and vertebrates using observational strategies, museum specimens and field reports. A variety of interacting processes generate an organism’s heterogeneous shapes, size, and structural features. Inclusion of ecology and environmental sciences will enrich students with our world which is crucial for human well being and prosperity. This section will provide new knowledge of the interdependence between people and nature that is vital for food production, maintaining clean air and water, and sustaining biodiversity in a changing climate. Students will also come to know about the basic principle of life, how a cell divides leading to the growth of an organism and also reproduces to form new organisms. The basic concepts of biosystematics, evolutionary biology and biodiversity will enable students to solve the biological problems related to environment. At the end of the course the students will be capable enough to comprehend the reason behind such a huge diversity of animals and reason out why two animals are grouped together or remain separate due to similarities and differences which exist at many levels along with ecological, environmental and cellular inputs. The Degree courses will enable students to go for higher studies like Masters and Ph.D in Zoology and Allied subjects.
6
Programme/Class: Certificate Subject: ZOOLOGY Course Code: B050101T
Year: First
Semester: First
Course Title: Cytology, Genetics and Infectious Diseases
Course outcomes:
The student at the completion of the course will be able to:
Understand the structure and function of all the cell organelles.
Know about the chromatin structure and its location.
To be familiar with the basic principle of life, how a cell divides leading to the growth of an organism
and also reproduces to form new organisms.
How one cell communicates with its neighboring cells?
Understand the basic principles of genetics and how genes (earlier called factors) are inherited from
one generation to another.
Understand the Mendel’s laws and the deviations from conventional patterns of inheritance.
Comprehend how environment plays an important role by interacting with genetic factors.
How to detect chromosomal aberrations in humans and study the pattern of inheritance by pedigree
analysis in families.
Credits: 4
Core:Compulsory
Max. Marks: 25+75
Min. Passing Marks: as per rules
Total No. of Lectures-Tutorials-Practical (in hours per week): L-T-P:4-0-0
Unit
Topics
Total No. of
Lectures (60)
I
Structure and Function of Cell Organelles I
6
Plasma membrane: chemical structure—lipids and proteins
Cell-cell interaction: cell adhesion molecules, cellular junctions
Endomembrane system: protein targeting and sorting, endocytosis,
exocytosis
Introduction to all national and international Biologists (Zoologists) who have contributed/contributing to Zoological and Life Sciences as a mark of tribute to ancient and modern biology will be included
as part of the Continuous Internal Evaluation (CIE)
II
Structure and Function of Cell Organelles II
6
Cytoskeleton: microtubules, microfilaments, intermediate filaments
Mitochondria: Structure, oxidative phosphorylation
Peroxisome and ribosome: structure and function
III
Nucleus and Chromatin Structure
8
Structure and function of nucleus in eukaryotes
Chemical structure and base composition of DNA and RNA
DNA supercoiling, chromatin organization, structure of
chromosomes
Types of DNA and RNA
7
IV
Cell cycle, Cell Division and Cell Signalling
8
Cell division: mitosis and meiosis
Cell cycle and its regulation, apoptosis
Signal transduction: intracellular signaling and cell surface receptors,
via G-protein linked receptors, JAK-STAT pathway
V
Mendelism and Sex Determination
8
Basic principles of heredity: Mendel’s laws, monohybrid and
dihybrid crosses
Complete and Incomplete Dominance
Penetrance and expressivity
Genic Sex-Determining Systems, Environmental Sex Determination,
Sex Determination in Drosophila, Sex Determination in Humans
Sex-linked characteristics and Dosage compensation
VI
Extensions of Mendelism, Genes and Environment
8
Extensions of Mendelism: Multiple Alleles, Gene Interaction
The Interaction Between Sex and Heredity: Sex-Influenced and Sex-
Limited Characteristics
Cytoplasmic Inheritance, Genetic Maternal Effects
Genomic Imprinting, Anticipation
Interaction Between Genes and Environment: Environmental Effects
on Gene Expression, Inheritance of Continuous Characteristics
VII
Human Chromosomes and Patterns of Inheritance
8
Human karyotype
Chromosomal anomalies: Structural and numerical aberrations with
examples
Pedigree analysis
Patterns of inheritance: autosomal dominant, autosomal recessive, X-linked recessive, X-linked dominant
VIII
Infectious Diseases
8
Introduction to pathogenic organisms: viruses, bacteria, fungi,
protozoa, and worms.
Structure, life cycle, pathogenicity, including diseases, causes,
symptoms and control of common parasites: Trypanosoma, Giardia
and Wuchereria
Suggested Readings:
1. Lodish et al: Molecular Cell Biology: Freeman & Co, USA (2004). 2. Alberts et al: Molecular Biology of the Cell: Garland (2002). 3. Cooper: Cell: A Molecular Approach: ASM Press (2000). 4. Karp: Cell and Molecular Biology: Wiley (2002). Pierce B. Genetics. Freeman (2004). 5. Lewin B. Genes VIII. Pearson (2004). 6. Watson et al. Molecular Biology of the Gene. Pearson (2004). 7. Thomas J. Kindt, Richard A. Goldsby, Barbara A. Osborne, Janis KubyKuby Immunology. W H
Freeman (2007). 8. Delves Peter J., Martin Seamus J., Burton Dennis R., Roitt Ivan M. Roitt's Essential Immunology,
13th Edition. Wiley Blackwell (2017). 9. Shetty Nandini Immunology Introductory Textbook. New Age International. (2005)
8
Course Books published in Hindi may be prescribed by the Universities and Colleges Course prerequisites: To study this course, a student must have had the subject biology in class/12th
Suggested Continuous Evaluation Methods:
House Examination/Test: 10 Marks
Total Marks: 25
Written Assignment/Presentation/Project / Term Papers/Seminar: 10 Marks
Class performance/Participation: 5 Marks
Further Suggestions: None
At the End of the whole syllabus any remarks/ suggestions: None
9
Programme/Class: Certificate
Year: First
Semester: First
Subject: ZOOLOGY
Course Code: B050102P
Course Title: Cell Biology & Cytogenetics Lab
Course outcomes:
At the completion of the course students will learn Hands-on:
1. To use simple and compound microscopes.
2. To prepare slides and stain them to see the cell organelles.
3. To be familiar with the basic principle of life, how a cell divides leading to the growth of an organism
and also reproduces to form new organisms.
4. The chromosomal aberrations by preparing karyotypes.
5. How chromosomal aberrations are inherited in humans by pedigree analysis in families.
6. The antigen-antibody reaction.
Credits: 2
Core:Compulsory
Max. Marks: 25+75
Min. Passing Marks: as per rules
Total No. of Lectures-Tutorials-Practical (in hours per week): L-T-P:0-0-4
Unit
Topics
Total No. of
Lectures (60)
I
1. To study different cell typessuch asbuccal epithelial cells, neurons,
15
striated muscle cells using Methylene blue.
2. To study the different stages of Mitosis in root tip of onion.
3. To study the different stages of Meiosis in grasshopper testis.
4. To prepare molecular models of nucleotides, amino acids, dipeptides
using bead and stick method.
5. To check the permeability of cells using salt solution of different
concentrations.
II
1. Study of parasites (eg. Protozoans, helminths etc.) from permanent
15
slides.
2. To learn the procedures for preparation of temporary and permanent
stained/unstained slides.
III
1. Study of mutant phenotypes of Drosophila.
15
2. Preparation of polytene chromosomes.
3. Study of sex chromatin (Barr bodies) in buccal smear and hair bud
cells (Human).
4. Preparation of human karyotype and study the chromosomal
aberrations with respect to number, translocation, deletion etc.
from the pictures provided.
5. To prepare family pedigrees.
IV
Virtual Labs (Suggestive sites)
15
https://www.vlab.co.in
https://zoologysan.blogspot.com
www.vlab.iitb.ac.in/vlab
www.onlinelabs.in
www.powershow.com
https://vlab.amrita.edu
https://sites.dartmouth.edu
10
National Education Policy-2020
Common Minimum Syllabus for all UP State Universities and Colleges For First Three Years of Higher Education (UG)
Proposed Titles for Theory and Practical Papers Under Graduate Programme SUBJECT: ZOOLOGY
Dr. Monisha Banerjee Professor& Dean Research Molecular & Human Genetics Lab
Department of Zoology University of Lucknow, Lucknow
Dr. Samar Vir Singh Rathore Assistant Professor
Department of Zoology St. John’s College Agra, UP
1
Dr. Praveen Ojha Sr. Assistant Professor Department of Zoology Kishori Raman PG College
Mathura, UP
Name
Designation
Steering Committee
Mrs. Monika S. Garg, (I.A.S.) Additional Chief Secretary
Chairperson Steering
Committee
Prof. Poonam Tandan
Professor,
Dept. of Physics
Prof. Hare Krishna
Professor,
Dept. of Statistics
Dr. Dinesh C. Sharma
Associate Professor,
Dept. of Zoology
Supervisory Committee-Science Faculty
Dr. Vijay Kumar Singh
Associate Professor,
Dept. of Zoology
Dr. Santosh Singh
Dean,
Dept. of Agriculture
Dr. Baby Tabussam
Associate Professor,
Dept. of Zoology
Dr. Sanjay Jain
Associate Professor,
Dept. of Statistics
Syllabus Developed by:
Affiliation Dept. of Higher Education U.P., Lucknow
Lucknow University, U.P. CCS University Meerut, U.P. K.M. Govt. Girls P.G. College Badalpur, G.B. Nagar, U.P. Agra College, Agra Mahatma Gandhi Kashi Vidhyapeeth, Varanasi Govt. Raza P.G. College Rampur, U.P. St. John’s College, Agra
S.No. 1.
2. 3.
Name
Designation
Department College/University
Dr. Monisha Banerjee
Professor & Dean,
Zoology
University of Lucknow,
Research
Lucknow
Dr. Samar Vir Singh Rathore Assistant Professor
Zoology
St. John’s College, Agra
Dr. Praveen Ojha
Assistant Professor
Zoology
Kishori Raman PG College,
Mathura
Semester-wise Titles of the Papers in B.Sc (Zoology)
Year Sem.
1
I
II
2
III
IV
3
V
VI
Course Code B050101T B050102P B050201T B050202P/R
B050301T B050302P B050401T
B050402P/R
B050501T
B050502T B050503P
B050601T B050602T B050603P
Paper Title Cytology, Genetics and Infectious Diseases
Cell Biology and Cytogenetics Lab Biochemistry and Physiology Physiological, Biochemical &Hematology Lab
Molecular Biology, Bioinstrumentation &Biotechniques Bioinstrumentation& Molecular Biology Lab Gene Technology, Immunology and Computational Biology Genetic Engineering and Counselling Lab
Diversity of Non-Chordates, Parasitology and Economic Zoology Diversity of Chordates and Comparative Anatomy Lab on Virtual Dissection, Anatomy, Economic Zoology and Parasitology Evolutionary and Developmental Biology Ecology, Ethology, Environmental Science and Wildlife Lab on Environmental Science, Behavioral Ecology, Developmental Biology, Wildlife, Ethology
Theory/Practical Theory
Practical Theory Practical/Field work Theory Practical Theory
Practical/Field work Theory
Theory Practical
Theory Theory Practical
Credits 04 02 04 02
04 02 04
02
04
04 02
04 04 02
2
Proposed Year wise Structure of UG Program in Zoology
Programme/Year
1 Certificate Course in
Medical Diagnostics & Public Health
Semester I
II
Course Codes B050101T
B050102P B050201T
B050202P/R
Paper Title
Cytology, Genetics and Infectious Diseases Cell Biology & Cytogenetics Lab Biochemistry and Physiology
Physiological, Biochemical &Hematology Lab
Credits 04 02 04
02
2 Diploma in Molecular Diagnostics and
Genetic Counselling
3 Degree in Bachelor of Science
B050301T
Molecular Biology,
Bioinstrumentation &
04
III
Biotechniques
B050302P
Bioinstrumentation &
Molecular Biology Lab
02
B050401T
Gene Technology, Immunology
and Computational Biology
04
IV
B050402P/R Genetic Engineering and
Counselling Lab
02
B050501T
Diversity of Non-Chordates,
Parasitology and Economic
04
Zoology
V
B050502T
Diversity of Chordates and
Comparative Anatomy
04
B050503P
Lab on Virtual Dissection,
Anatomy, Economic Zoology 02
and Parasitology
B050601T
Evolutionary and
Developmental Biology
04
VI
B050602T
Ecology, Ethology,
Environmental Science and
04
Wildlife
B050603P
Lab on Environmental Science,
Behavioral Ecology,
Developmental Biology,
02
Wildlife, Ethology
Teaching Hours
60 60 60 60
60 60 60 60 60 60 60
60
60
60
3
Subject prerequisite To study Zoology in undergraduate, a student must have studied Biology, Biotechnology or Life Science in Class 12.
Programme Objectives (POs)
1. The programme has been designed in such a way so that the students get the flavour of both classical and modern aspects of Zoology/Animal Sciences. It aims to enable the students to study animal diversity in Indian subcontinent, environmental science and behavioural ecology.
2. The modern areas including cell biology and genetics, molecular biology, biochemistry, physiology followed by biostatistics, Evolutionary biology, bioinformatics and genetic engineering have been included to make the study of animals more interesting and relevant to human studies which is the requirement in recent times.
3. The lab courses have been designed in such a way that students will be trained to join public or private labs.
PSO1
PSO 2 PSO 3 PSO 4
PSO 5
Certificate Course in Medical Diagnostics & Public Health
B.Sc I Programme Specific Outcomes (PSOs) This course introduces System Biology and various functional components of an organism. Emphasis will be on physiological understanding abnormalities and anomalies associated with white blood cells and red blood cells. The course emphasizes cell identification, cell differentiation and cell morphology evaluation procedures. This will enhance hematology analytical skills along with skill of using many instruments. The students will learn the basic principles of genetics and how to prepare karyotypes to study the chromosomes. How chromosomal aberrations are inherited in humans by pedigree analysis in families. The students will have hands-on training in the techniques like microscopy, centrifugation and chromatography, and various biochemical techniques, preparation of slides which will help them in getting employment in pathology labs and contribute to health care system. The Certificate courses will enable students to apply for technical positions in government and private labs/institutes.
4
PSO1 PSO 2 PSO 3 PSO 4
PSO 5
Diploma in Molecular Diagnostics and Genetic Counselling
B.Sc II Programme Specific Outcomes (PSOs) The student at the completion of the course will be able to have a detailed and conceptual understanding of molecular processes viz. DNA to trait. The differential regulation of genes in prokaryotes and eukaryotes leads to the development of an organism from an embryo. The students will be able to understand and apply the principles and techniques of molecular biology which prepares students for further career in molecular biology. Independently execute a laboratory experiment using the standard methods and techniques. The principles of genetic engineering, gene cloning, immunology and related technologies will enable students to play an important role in applications of biotechnology in various fields like agriculture, forensic sciences, industry and human health and make a career out of it. Students can have their own start-ups as well. The basic tools of bioinformatics will enable students to analyze large amount of genomic data and its application to evolutionary biology.Apply knowledge and awareness of the basic principles and concepts of biology, computer science and mathematics existing software effectively to extract information from large databases and to use this information in computer modeling. The Diploma courses will ensure employability in Hospitals/Diagnostics and Pathology labs with good hands-on training. It will also enable students to take up higher studies and Research as their career and work in renowned labs in the country and abroad.
5
PSO1 PSO 2 PSO 3
PSO 4 PSO 5 PSO 6
PSO 7
Degree in Bachelor of Science
B.Sc III Programme Specific Outcomes (PSOs) This programme aims to introduce students to animal diversity of
invertebrates and vertebrates. The students will be taught about invertebrates and vertebrates using observational strategies, museum specimens and field reports. A variety of interacting processes generate an organism’s heterogeneous shapes, size, and structural features. Inclusion of ecology and environmental sciences will enrich students with our world which is crucial for human well being and prosperity. This section will provide new knowledge of the interdependence between people and nature that is vital for food production, maintaining clean air and water, and sustaining biodiversity in a changing climate. Students will also come to know about the basic principle of life, how a cell divides leading to the growth of an organism and also reproduces to form new organisms. The basic concepts of biosystematics, evolutionary biology and biodiversity will enable students to solve the biological problems related to environment. At the end of the course the students will be capable enough to comprehend the reason behind such a huge diversity of animals and reason out why two animals are grouped together or remain separate due to similarities and differences which exist at many levels along with ecological, environmental and cellular inputs. The Degree courses will enable students to go for higher studies like Masters and Ph.D in Zoology and Allied subjects.
6
Programme/Class: Certificate Subject: ZOOLOGY Course Code: B050101T
Year: First
Semester: First
Course Title: Cytology, Genetics and Infectious Diseases
Course outcomes:
The student at the completion of the course will be able to:
Understand the structure and function of all the cell organelles.
Know about the chromatin structure and its location.
To be familiar with the basic principle of life, how a cell divides leading to the growth of an organism
and also reproduces to form new organisms.
How one cell communicates with its neighboring cells?
Understand the basic principles of genetics and how genes (earlier called factors) are inherited from
one generation to another.
Understand the Mendel’s laws and the deviations from conventional patterns of inheritance.
Comprehend how environment plays an important role by interacting with genetic factors.
How to detect chromosomal aberrations in humans and study the pattern of inheritance by pedigree
analysis in families.
Credits: 4
Core:Compulsory
Max. Marks: 25+75
Min. Passing Marks: as per rules
Total No. of Lectures-Tutorials-Practical (in hours per week): L-T-P:4-0-0
Unit
Topics
Total No. of
Lectures (60)
I
Structure and Function of Cell Organelles I
6
Plasma membrane: chemical structure—lipids and proteins
Cell-cell interaction: cell adhesion molecules, cellular junctions
Endomembrane system: protein targeting and sorting, endocytosis,
exocytosis
Introduction to all national and international Biologists (Zoologists) who have contributed/contributing to Zoological and Life Sciences as a mark of tribute to ancient and modern biology will be included
as part of the Continuous Internal Evaluation (CIE)
II
Structure and Function of Cell Organelles II
6
Cytoskeleton: microtubules, microfilaments, intermediate filaments
Mitochondria: Structure, oxidative phosphorylation
Peroxisome and ribosome: structure and function
III
Nucleus and Chromatin Structure
8
Structure and function of nucleus in eukaryotes
Chemical structure and base composition of DNA and RNA
DNA supercoiling, chromatin organization, structure of
chromosomes
Types of DNA and RNA
7
IV
Cell cycle, Cell Division and Cell Signalling
8
Cell division: mitosis and meiosis
Cell cycle and its regulation, apoptosis
Signal transduction: intracellular signaling and cell surface receptors,
via G-protein linked receptors, JAK-STAT pathway
V
Mendelism and Sex Determination
8
Basic principles of heredity: Mendel’s laws, monohybrid and
dihybrid crosses
Complete and Incomplete Dominance
Penetrance and expressivity
Genic Sex-Determining Systems, Environmental Sex Determination,
Sex Determination in Drosophila, Sex Determination in Humans
Sex-linked characteristics and Dosage compensation
VI
Extensions of Mendelism, Genes and Environment
8
Extensions of Mendelism: Multiple Alleles, Gene Interaction
The Interaction Between Sex and Heredity: Sex-Influenced and Sex-
Limited Characteristics
Cytoplasmic Inheritance, Genetic Maternal Effects
Genomic Imprinting, Anticipation
Interaction Between Genes and Environment: Environmental Effects
on Gene Expression, Inheritance of Continuous Characteristics
VII
Human Chromosomes and Patterns of Inheritance
8
Human karyotype
Chromosomal anomalies: Structural and numerical aberrations with
examples
Pedigree analysis
Patterns of inheritance: autosomal dominant, autosomal recessive, X-linked recessive, X-linked dominant
VIII
Infectious Diseases
8
Introduction to pathogenic organisms: viruses, bacteria, fungi,
protozoa, and worms.
Structure, life cycle, pathogenicity, including diseases, causes,
symptoms and control of common parasites: Trypanosoma, Giardia
and Wuchereria
Suggested Readings:
1. Lodish et al: Molecular Cell Biology: Freeman & Co, USA (2004). 2. Alberts et al: Molecular Biology of the Cell: Garland (2002). 3. Cooper: Cell: A Molecular Approach: ASM Press (2000). 4. Karp: Cell and Molecular Biology: Wiley (2002). Pierce B. Genetics. Freeman (2004). 5. Lewin B. Genes VIII. Pearson (2004). 6. Watson et al. Molecular Biology of the Gene. Pearson (2004). 7. Thomas J. Kindt, Richard A. Goldsby, Barbara A. Osborne, Janis KubyKuby Immunology. W H
Freeman (2007). 8. Delves Peter J., Martin Seamus J., Burton Dennis R., Roitt Ivan M. Roitt's Essential Immunology,
13th Edition. Wiley Blackwell (2017). 9. Shetty Nandini Immunology Introductory Textbook. New Age International. (2005)
8
Course Books published in Hindi may be prescribed by the Universities and Colleges Course prerequisites: To study this course, a student must have had the subject biology in class/12th
Suggested Continuous Evaluation Methods:
House Examination/Test: 10 Marks
Total Marks: 25
Written Assignment/Presentation/Project / Term Papers/Seminar: 10 Marks
Class performance/Participation: 5 Marks
Further Suggestions: None
At the End of the whole syllabus any remarks/ suggestions: None
9
Programme/Class: Certificate
Year: First
Semester: First
Subject: ZOOLOGY
Course Code: B050102P
Course Title: Cell Biology & Cytogenetics Lab
Course outcomes:
At the completion of the course students will learn Hands-on:
1. To use simple and compound microscopes.
2. To prepare slides and stain them to see the cell organelles.
3. To be familiar with the basic principle of life, how a cell divides leading to the growth of an organism
and also reproduces to form new organisms.
4. The chromosomal aberrations by preparing karyotypes.
5. How chromosomal aberrations are inherited in humans by pedigree analysis in families.
6. The antigen-antibody reaction.
Credits: 2
Core:Compulsory
Max. Marks: 25+75
Min. Passing Marks: as per rules
Total No. of Lectures-Tutorials-Practical (in hours per week): L-T-P:0-0-4
Unit
Topics
Total No. of
Lectures (60)
I
1. To study different cell typessuch asbuccal epithelial cells, neurons,
15
striated muscle cells using Methylene blue.
2. To study the different stages of Mitosis in root tip of onion.
3. To study the different stages of Meiosis in grasshopper testis.
4. To prepare molecular models of nucleotides, amino acids, dipeptides
using bead and stick method.
5. To check the permeability of cells using salt solution of different
concentrations.
II
1. Study of parasites (eg. Protozoans, helminths etc.) from permanent
15
slides.
2. To learn the procedures for preparation of temporary and permanent
stained/unstained slides.
III
1. Study of mutant phenotypes of Drosophila.
15
2. Preparation of polytene chromosomes.
3. Study of sex chromatin (Barr bodies) in buccal smear and hair bud
cells (Human).
4. Preparation of human karyotype and study the chromosomal
aberrations with respect to number, translocation, deletion etc.
from the pictures provided.
5. To prepare family pedigrees.
IV
Virtual Labs (Suggestive sites)
15
https://www.vlab.co.in
https://zoologysan.blogspot.com
www.vlab.iitb.ac.in/vlab
www.onlinelabs.in
www.powershow.com
https://vlab.amrita.edu
https://sites.dartmouth.edu
10
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